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Sleep Board Review Test 126. Which of the following medications
suppresses REM sleep? a. modafinil b. caffeine c. venlafaxine d. zolpidem e. zaleplon Answer: c. venlafaxine Venlafaxine is a serotonin and norepinephrine
reuptake inhibitor which suppresses REM sleep. Modafinil is a wake-promoting agent
which does not suppress REM sleep.
Caffeine is a methlyxanthine which affects
sleep as an adenosine receptor antagonist. Zolpidem and
zaleplon are both non-nezodiazepine
benzodiazepine receptor agonists which do not suppress REM sleep when used at
recommended doses. Reference: Resp Care Clin 2006;12:81 |
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