Sleep Board Review Test 1

2. The secretion of which of the following is inhibited by sleep?

a. TSH

b. cortisol

c. ACTH

d. Insulin like growth factor

e. none of the above

Answer: a. TSH

TSH secretion is inhibited during sleep. TSH levels are lowest during the day and increase to a maximum just prior to sleep onset. Sleep deprivation will lead to an increase in TSH level (about double). Arousals lead to transient increases in TSH levels.

Reference:

Bowman TJ. Review of Sleep Medicine, Butterworth-Heineman Medical 2002, Chapter 3

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