Sleep Board Review Test 1

17. Which of the following medication suppresses REM sleep?

a. phenelzine

b. buproprion

c. nefazodone

d. a + b

e. a, b + c

Answer: a. phenelzine

Phenelzine is a monoamine oxidase inhibitor (MAOI). Most antidepressants are REM suppressing agents, however the MAOIs are the most potent REM suppressors. Buproprion and nefazodone do not suppress REM sleep

Reference:

Kryger et al, Principles and Practice of Sleep Medicine, 4^th edition, 2005; pages 500-1.

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